• Support drug product development, process transfer, and scale-up activities.
• Assess molecule developability and determine formulation screening strategies for biologics, ADCs and other biologics modalities.
• Develop robust fill-finish manufacturing processes for liquid and lyophilized drug products in vials, pre-filled syringes and other novel primary packaging formats.
• Establish preclinical and clinical dose preparation and administration protocols for drug products.
• Analyze and trend stability data to understand product degradation pathways and inform development strategy.
• Author and/or review technical protocols, reports, and documentaiton to support development activities and technology transfer.
• Perform wet-lab activities as needed to support program objectives.
• Located on-site at our Boston Seaport location.

• Master’s or PhD in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, or a related discipline, with 3-5 years of industry experience, or equivalent years of education and experience; a PhD with 1-2 years of industry experience, or equivalent years of education and experience.
• Direct industry experience in biologics drug product development.

• Hands-on experience in formulation development for recombinant proteins, including antibodies, ADCs, and fusion proteins.
• Experience developing stable, high-concentration liquid formulations and dosage forms for biologics.
• Experience developing aseptic fill-finish manufacturing processes for biologic drug products in vial, pre-filled syringe, and cartridge formats.
• Experience using analytical techniques to characterize physical and chemical properties of biologics.
• Knowledge of cGMPs and regulatory guidelines for biologics.
• Familiarity with biologics upstream and downstream processes.
• Strong data analysis, technical writing, and scientific communication skills

This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements

If you do not agree with the Atrium Terms and Conditions, you can still complete your application for this position by emailing your resume to our team at tempstaffing@vrtx.com. Please include the job title in the subject of your email.