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The Department of Urology has an exciting opportunity for a full-time Senior Bioinformatics Analyst work on-site in Miami.

DEPARTMENT ADDENDUM

Department Specific Functions

The Sharifi Laboratory is seeking a highly motivated Bioinformatics Analyst to support translational and mechanistic studies focused on prostate cancer progression, steroid metabolism, androgen signaling, therapeutic resistance, and biomarker discovery. The successful candidate will work closely with laboratory scientists and clinicians to analyze genomic, transcriptomic, epigenomic, metabolomic, and clinical datasets and contribute to high-impact cancer research.

• Design, implement, and maintain computational workflows for analysis of high-throughput metabolomics, sequencing and multi-omic datasets.

• Analyze spatial transcriptomics, proteomic, metabolomic, and clinical data.

• Integrate molecular and clinical datasets to identify biomarkers associated with treatment response, disease progression, and patient outcomes.

• Perform statistical analyses and develop reproducible pipelines using modern bioinformatics tools and programming languages.

• Contribute to studies investigating androgen biosynthesis, steroid metabolism, androgen receptor signaling, and mechanisms of therapeutic resistance in prostate cancer.

• Support analysis of patient-derived datasets, clinical cohorts, and public cancer genomics resources including TCGA, cBioPortal, GEO, dbGaP, and other consortium datasets.

• Develop data visualization tools and generate publication-quality figures and reports.

• Collaborate with laboratory investigators on experimental design, data interpretation, and manuscript preparation.

• Maintain rigorous standards for reproducible research, version control, documentation, and data management.

• Assist in preparation of grant applications, progress reports, and scientific presentations.

Department Specific Qualifications

• Bachelor’s degree in relevant field required, M.S. or Ph.D. preferred

• Demonstrated experience analyzing metabolomics and next-generation sequencing data.

• Strong programming skills in R and/or Python.

• Proficiency with bioinformatics software and workflow frameworks.

• Strong understanding of statistics and experimental design.

• Ability to work independently and collaboratively within a multidisciplinary research environment.

• Excellent written and verbal communication skills.

• Candidates with biochemistry and chemistry background is preferred.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.

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