Notifications

Ultragenyx
3.4
Executive Director, CMC QA
South San Francisco, CA
$294K - $363K (Employer provided)
Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.…
17d
Ultragenyx
3.4
Executive Director, CMC QA
Novato, CA
$294K - $363K (Employer provided)
Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.…
17d
Wallace Electric
4.5
Commercial and Industrial Electrical Project Executive
Atlanta, GA
$150K - $175K (Employer provided)
Easy Apply
*Master Electrician License* or equivalent state electrical license. *DBIA Design-Build Professional™* certification (preferred for design-build project……
5d
Knothe & Bruce Architects
5.0
Associate Architect / Architect IV - Project Architect - Onsite in Madison, WI
Middleton, WI
$90K - $121K (Employer provided)
Easy Apply
Serving as contact for the field during construction administration. Leading project analysis, project profile, and site analysis during initial phase of……
30d+
Led Sign Solutions
Estimator/Project Manager for a sign company
Salt Lake City, UT
$62K - $74K (Employer provided)
Easy Apply
Develop accurate cost estimates by analyzing project requirements, specifications, and vendor proposals, utilizing tools such as Excel data analysis and ERP……
24d
Titan Asset Management
Maintenance Manager
Rochester, MN
$77K - $115K (Glassdoor est.)
Easy Apply
Valid driver's license with an acceptable driving record. Coordinate repairs involving HVAC, plumbing, electrical, mechanical, lighting, doors, roofing, and……
25d
Knothe & Bruce Architects
5.0
Associate Architect / Architect III - Project Architect - Onsite in Madison, WI
Middleton, WI
$77K - $101K (Employer provided)
Easy Apply
Serving as a contact for the field during construction administration. Leading project analysis, project profile, and site analysis during initial phase of……
30d+
Wausau Supply Company
3.4
Siding Specialist- Eastern Dakotas/Western MN
Rochester, MN
Travel within geography, making calls on contractors, remodelers & architects. Your role combines product knowledge on all assigned brands, field engagement,……
30d+
BASF
3.8
Account Manager - Beauty Care Solutions
Florham Park, NJ
$128K - $160K (Employer provided)
Hold a bachelor's degree in biology, biochemistry, or related field; Advanced degree is preferred. Identifying, qualifying, and driving new business……
30d+
Spinnaker Trust
Senior Relationship Administrator
Portland, ME
$60K - $75K (Employer provided)
Easy Apply
The ideal candidate will have at least 5 years of experience in the wealth management industry and strong technical skills.…
25d
Victaulic
3.4
Engineering Manager, Tools Technology
Easton, PA
$91K - $130K (Glassdoor est.)
This role leads the mechanical development of new pipe preparation tools — spanning roll grooving, cut grooving, hole cutting, and specialty tools — as well as……
26d
Calgon Carbon
3.6
Sr. Maintenance Tech - NTP
North Tonawanda, NY
$33.92 - $36.41 Per Hour (Employer provided)
Easy Apply
A valid driver's license is required. The Sr. Maintenance Technician supervises others as required in the repair and maintenance of plant equipment and……
9d
JEM Wellness Brands
5.0
Personal Training Manager
Easy Apply
If you do not currently hold a nationally accredited personal training certification and/or a degree in Kinesiology, you must obtain one nationally accredited……
26d
AdventHealth Corporate Services
Manager Clinical Pharmacy Specialty and Ambulatory Care
Denver, CO
$137K - $255K (Employer provided)
Easy Apply
This position performs all functions of a registered pharmacist, including accurate and timely dispensing, clinical interaction with the healthcare team,……
9d
Kept Companies
2.8
Inside Sales Manager
Tampa, FL
$55K - $60K (Employer provided)
Easy Apply
The successful candidate will play a critical role in driving revenue growth, improving close rates, and creating a performance-driven sales culture.…
30d+
Teck Resources Limited
4.0
Senior Engineer, Tailings and Closure
Idaho
$101K - $131K (Employer provided)
Provide geotechnical and geoenvironmental technical leadership for tailings and water-retaining structures, including support for investigations, construction,……
20d
Hotel Equities
3.6
Maintenance Technician Holiday Inn Bismarck ND
Bismarck, ND
$16.00 - $18.00 Per Hour (Employer provided)
Easy Apply
Working knowledge of federal, state and local laws governing equal employment opportunity and civil rights, occupational safety and health, wage and hour issues……
6d
TargetPath
4.4
Amazon Account Manager
Wilsonville, OR
Easy Apply
Bachelor's degree in Business, Marketing, Ecommerce, or a related field preferred; equivalent professional experience considered.…
30d+
Teya Enterprises, LLC
Project Manager – Facilities Operations & Maintenance
San Luis, AZ
$100K - $120K (Employer provided)
Easy Apply
Manage and respond to service calls, emergencies, and after-hours support as needed. Conduct routine facility inspections, develop corrective action plans, and……
5d
Grand Traverse Refrigeration
Account Manager - HVAC/R
Traverse City, MI
$65K - $80K (Employer provided)
Easy Apply
Ability to navigate industrial or commercial facilities as needed, including climbing stairs, accessing mechanical rooms, and climbing ladders when required.…
12d
GEA Group
3.8
Market Manager - Liquid Dairy
Hudson, WI
$57K - $102K (Glassdoor est.)
Coordinate cross-functional actions with Sales, Strategy, Engineering, Operations, Procurement, Business Line and local contractors to improve competitiveness,……
24h
Terracon
3.8
Materials Department Manager
Lubbock, TX
$48K - $83K (Glassdoor est.)
A valid driver’s license with acceptable violation history may be required. Prepare designs and work specifications; develop schedules, budgets and forecasts;……
16d
JEM Wellness Brands
5.0
Personal Trainer
Folsom, CA
$16.90 Per Hour (Employer provided)
Easy Apply
If you do not currently hold a nationally accredited personal training certification and/or a degree in Kinesiology, you must obtain one nationally accredited……
30d+
Department of Labor Federal Credit Union
3.2
Loan Servicing and Collections Manager
United States
$75K - $80K (Employer provided)
Easy Apply
Ensure servicing and collection activities comply with applicable laws and regulations, including FDCPA, BSA/AML, OFAC, and state requirements.…
30d
Ausonio
4.2
Senior Project Manager for Commercial Construction (15+ Years of PM Experience)
Castroville, CA
$150K - $190K (Employer provided)
Easy Apply
The ideal candidate will bring *15+ years of diverse project management experience* and a track record of *leading and developing high-performing teams of……
30d+
Overlake Arthritis and Osteoporosis Center
4.0
Clinical Trial Manager
Bellevue, WA
$90K - $120K (Employer provided)
Easy Apply
Teaching/research medical license in Washington State (Required). Develop, manage, and monitor clinical trial budgets; negotiate site payments, track……
30d+
Buzzi Unicem USA
3.4
Manager Strategic Commodities & Energy
Festus, MO
Bachelor's degree in Supply Chain Management, Business Administration, Finance, Engineering, or a related field; or equivalent relevant professional work……
30d+
AMIP Management
4.1
Loan Resolution Specialist
Lake Forest, CA
$75K - $100K (Employer provided)
Easy Apply
Subject matter expertise: asset management, non-performing loans, all loan retention options (i.e. Modifications), all non-retention options (i.e. DILs),……
30d+
Confidential
Director, Client Sales and Insights
Riverside, CA
$80K - $100K (Employer provided)
Easy Apply
Run all client-facing project touchpoints: kickoff calls, mid-project status updates, final delivery presentations. Project scoping and delivery discipline.…
4d
Prestige Beauty Company
Project Manager – Beauty & Fragrance (Product Launch & Operations)
Plantation, FL
$65K - $80K (Employer provided)
Easy Apply
Own end-to-end program timelines with suppliers, proactively managing risks, resolving issues, and driving accountability.…
30d+

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won't go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

The Executive Director, CMC QA will provide strategic, operational, and technical quality leadership across all Ultragenyx programs inclusive of biologics, small molecule, gene therapy, and ASO. This leader will oversee CMC QA responsibilities spanning program QA and CMO QA for starting materials, drug substance, and drug product, ensuring phase-appropriate and commercially robust quality oversight from development through lifecycle management. The role will lead and develop a team of approximately 8–12 quality professionals, partner closely with Technical Operations, Product Development, Supply Chain, Regulatory, and Quality stakeholders, and represent CMC QA in governance forums, inspections, regulatory submissions, and external partner interactions.

Work Model:

Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

If an employer includes a salary or salary range on their job, we display it as "Employer Provided". If a job has no salary data, Glassdoor displays a "Glassdoor Estimate" if available. To learn more about "Glassdoor Estimates," see our FAQ page.

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

Work Model:

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

77,735 Program and portfolio manager jobs in United States

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret