Pros
A personal pride that comes with knowing you work for Genentech. The satisfaction of feeling like you can actually take part in rather senior level type of decisionmaking even if you are not at a senior level.
Cons
Officer level leadership treats employees like children, giving them virtually no input to the pedantic budget process or overall vision of the department. Sometimes I thought that the most senior management genuinely didn't understand technology. Even the simplest decisions like hiring mid-level staff have to go through extensive review at the VP level. Also, and the worst part -- senior management doesn't even know or care about the "bread and butter" services we provide, sometimes it's like these things are actively DISLIKED.