Good times and bad times - Principal Scientist Genentech Employee Review

4.0
Apr 19, 2025
Recommend
CEO approval
Business Outlook

Pros

Incredible pay and benefits Incredibly smart community of scientists

Cons

My first 3 years were incredible in gRED (the R&D side of Genentech). However the last 3 years have been a series of reorganizations in gRED and the end is nowhere in sight. Layoffs occur regularly and are always looming. It's understandable that changes need to be made because many of our blockbuster drugs have lost exclusivity and we don't have replacements to generate the lost profits (many recent phase 3 failures). However the eternal reorg/layoff cycle is soul crushing after 3 years.

Explore other reviews about Genentech

5.0
Jul 8, 2026
Recommend
CEO approval
Business Outlook

Pros

Great culture and work environment.

Cons

PhD is necessary oftentimes for advancement.

3.0
May 7, 2026
Recommend
CEO approval
Business Outlook

Pros

Genentech's origin story and mission are genuinely inspiring — few companies can point to such a meaningful historical arc in medicine. Patient engagement is taken seriously and feels authentic, not performative. The campus is beautiful and the culture has real warmth.

Cons

DDA is operating with significant gaps. First, the foundational data infrastructure is not mature enough to support the ambitions being set for the team. Second, the measurement culture has gotten ahead of the methodology, and no one in a position of authority seems to be asking hard questions about whether the numbers actually mean what they're being presented as meaning. Third, some management feel disconnected from the work itself, lacking the knowledge, hands-on experience, or relevant credentials. Individually any one of these would be manageable. Together these create an environment where it's hard to do rigorous work, rather work is performative, and be recognized for it.

3
See reviews by: Helpful|Rating|Date|All