1/ they suck at managing the skills pool during reorgs. They shuffle you around in ways that sometimes makes no sense at all. I've had 6 reorgs in 6 years (all justified from a business standpoint). I was just unlucky, always in the team that just got reorged, but it really slowed down your career.
2/ compensation is very uneven across the globe. US and Switzerland get employees get very well paid compared to, for example, UK employees. I've had greater changes of lifestyle and comp from changing country than I did from being promoted. A bit odd.
3/ in the sales org, there is a strong tendency to promote good presenters over doers.
4/ work life balance is...well it depends. i've had jobs where I was bored out of my mind and jobs when I worked until 10pm and on Sundays. It really depends. Overall good but very uneven.