Pros
Research positions here are quite nice, you don't have the stress of working at the hospital. UPMC also has an affordable health care plan, 14 days of upaid leave and seven holidays, so a total of 21 days off in a year for entry-level employees. Research Assistant positions also maintain normal workday hours (i.e. 8:30-5)
Cons
UPMC is a bit stingy with some of their other perks. For instance, they don't subsidize your parking fees or bus pass (there is an option to get a pre-tax bus pass from UPMC itself, but the process is incredibly tedious and only saves you about $7 a paycheck). Holiday time is also based on doctors' work schedules, so those working in non-clinical positions end up getting less holiday time than their counterparts in University of Pittsburgh-affiliated labs.