Pros
Cool but not proven science, great peers
Cons
Management is awful. ALL of them. They'll pretend to be your colleagues but when upper management says you're gone, none of them will talk to you anymore or answer questions like "why was I let go". I think they were wanting low paid post-docs and technicians as the new business model. The "core values" are BS. Management doesn't follow them. Middle management doesn't follow them. They'll also expect you to work 60-80 hrs/week. They can kick you out at some time of day but expect you to go home and work more. They used to pay for dinners if you worked late, they'll just make you go home and work. That was mentioned to me by upper management. It's a dysfunctional atmosphere. In subsequent interviews, I had potential employers say "we're not like Locus, we want our employees to be happy" and "yeah, I had employees who left to work there and wanted to come back because of the environment". Locus has a bad/dysfunctional reputation in RTP.