Pros
- Scientifically, excellent place. Here you have rare chance to learn from the best and do the best science, which in many cases is a guideline for big part of scientific community. - Financially, excellent place. A lot of opportunities to participate in different meetings, conferences; in most cases PI budgets allow for sophisticated experiments. - There are many biotech companies around. - Plenty of people from foreign countries is giving you an opportunity to learn and understand different cultures. - Sunny California, nice weather every day and walking distance to the ocean, Also not far from spectacular scenic views, national parks.
Cons
Perfect place, weather and ocean view. Maybe a little bit competitive and requires hard working but these are just minor things.